Berberine is an alkaloid extracted from various plants used in traditional Chinese medicine. It's primarily used to reduce insulin resistance and improve biomarkers of type II diabetes such as fasting glucose and glycated hemoglobin. Berberine can activate an enzyme called Adenosine Monophosphate-Activated Protein Kinase (AMPK) while inhibiting Protein-Tyrosine Phosphatase 1B (PTP1B), thus increasing insulin sensitivity. Other possible mechanisms of action include protecting and β-cells, regulating hepatic gluconeogenesis, and reducing inflammatory cytokine signaling.
Berberine HCL – Powder, 50g
Signal transducer and activator of transcription 3 (STAT3), peroxisome proliferator-activated receptor (PPAR)
Store at room temperature, tightly sealed, away from heat, light and moisture.
Soluble in Ethanol, DMSO
Yellow, flour like powder
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