CRL-40,940 (Flmodafinil), Powder

CRL-40,940, commonly known as Flmodafinil, is a modified analog of Modafinil and Adrafinil, two compounds known for their wakefulness-promoting effects. Flmodafinil has a similar structure but includes two fluorine atoms, which enhance its potency and bioavailability compared to Modafinil. This modification may result in more efficient absorption and a longer duration of action, making it a strong candidate for promoting sustained alertness, focus, and cognitive performance.

Flmodafinil works primarily by modulating the dopaminergic system, increasing dopamine levels in the brain through inhibition of the dopamine transporter (DAT). It also affects the hypothalamic pathways involved in the regulation of wakefulness and sleep. These actions result in increased mental alertness, improved focus, and enhanced cognitive function, particularly during extended periods of wakefulness or mental exertion.

Mechanism of Action:

Flmodafinil enhances cognitive performance and wakefulness by inhibiting the dopamine transporter (DAT), thereby increasing the availability of dopamine in the brain. Dopamine plays a critical role in mood regulation, motivation, and focus, and its increased presence supports heightened alertness and sustained cognitive performance.

• Dopamine Reuptake Inhibition: By inhibiting the reuptake of dopamine, Flmodafinil increases dopamine levels in the brain, improving motivation, focus, and mental clarity.
• Wakefulness Promotion: Flmodafinil’s effects on the hypothalamic pathways help regulate the sleep-wake cycle, making it effective for promoting wakefulness without causing significant overstimulation or jitteriness.also you can check this product flmodafinil-solution

Effects:

• Increased Wakefulness: Flmodafinil is recognized for its ability to promote wakefulness, making it suitable for extended periods of mental and physical exertion.
• Enhanced Focus and Cognitive Performance: By increasing dopamine levels, Flmodafinil supports improved focus, mental clarity, and sustained cognitive performance during demanding tasks.
• Long-Lasting Effects: The fluorination of the molecule enhances bioavailability and duration of action, potentially leading to more prolonged wakefulness and cognitive benefits compared to Modafinil.
• Low Risk of Overstimulation: Flmodafinil’s mechanism of action allows for heightened alertness and cognitive enhancement without the intense stimulation or jitteriness often associated with traditional stimulants.

Clinical Research:

• Wakefulness and Cognitive Function: Studies on Flmodafinil and its analogs have shown that these compounds promote wakefulness and improve cognitive function in both healthy and sleep-deprived conditions. Research by Battleday and Brem (2015) indicates that Modafinil enhances cognitive function in various tasks, and similar benefits are expected from Flmodafinil due to its structural similarity.
• Dopamine Modulation: Research on dopamine reuptake inhibitors (DAT inhibitors) suggests that compounds like Flmodafinil can enhance cognitive performance by increasing dopamine availability, which is linked to improved attention, motivation, and cognitive endurance.check our Pinterest

Additional Effects:

• Mood and Motivation: Flmodafinil’s effect on dopamine levels may positively influence mood and motivation, supporting a positive mental state during periods of extended wakefulness or cognitive demand.
• Cognitive Resilience: By supporting sustained focus and mental performance, Flmodafinil may help maintain cognitive resilience during tasks requiring prolonged attention or high levels of cognitive processing.

For a detailed lab analysis and comprehensive product specifications, please refer to the sections below.