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NSI-189 Phosphate

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NSI-189 Phosphate, Powder

NSI-189 is a benzylpiperizine-aminiopyridine, a novel chemical entity that stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in murine hippocampus in vivo. Emerging evidence also indicates that NSI-189 phosphate has regionally specific effects insofar as neurogenesis is observed largely in the subventricular zone of the hippocampus. Results from a preliminary proof of concept study suggests that NSI-189 may be capable of mitigating depressive symptoms and improve cognitive function in adults with DSM-5-defined Major Depressive Disorder (MDD).

Additional information


1g, 5g

Chemical Informations

NSI-189 Phosphate ā€“ Powder

Application TBA
CAS 1270138-41-4
Molar Mass 464.495 g/mol
Ā ChemicalĀ Formula C22H33N4O5P
IUPAC Name (4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone;phosphoric acid
Synonyms NSI-189, NSI189, NSI 189
Storage Room temperature
Solubility Not soluble in Water, Ethanol, PEG, PG, Glycerin
Organoleptic Profile White fine powder
Physical Form Solid
Specification ā‰„98%
Terms This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with ourĀ Terms & ConditionsĀ prior to ordering.

Lab Analysis


2310EURO.923A_NSI 189 PHOSPHATE LOT= 231129 (HNMR)

2211EURO.163I_NSI-189 Phosphate CAS=1270138-41-4 Lot=251022

2211EURO.163I NSI-189 Phosphate_CoA