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Sulbutiamine – Powder, 50g

Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) delivered in vegetarian capsules. As a dimer combining two modified thiamine molecules, it readily crosses the blood–brain barrier thus increasing levels of thiamine and thiamine phosphate esters in the brain. Sulbutiamine was developed in Japan by Taisho Pharmaceutical in 1965.

Sulbutiamine is a psychostimulant, the anti-asthenic and energising effects of which are the result of modification of the thiamine ring, the formation of a disulphide bridge, creation of a lipophilic ester and opening of the thiazole cycle. The resulting new lipophilic compound is therefore responsible for its valuable properties. Sulbutiamine’s main benefit lies in its ability to combat asthenia by selectively targeting the areas involved in the condition. Asthenia is essentially a form of chronic fatigue that is cerebral rather than neuromuscular in origin.

Additional information


20g, 50g

Chemical Informations

Application Dopamine modulator, lipophilic derivative of thiamine
CAS 3286-46-2
Molar Mass 702.9 g/mol
Chemical Formula C32H46N8O6S2
IUPAC Name [(Z)-4-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-3-[[(Z)-2-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-5-(2-methylpropanoyloxy)pent-2-en-3-yl]disulfanyl]pent-3-enyl] 2-methylpropanoate
Synonyms 2-isobutyrylthiamine disulfide, Arcalion, bis(2-(isobutyryloxy)ethyl-1-N-((4-amino-2-methylpyrimidin-5-yl)methyl)formamido-2-propene-1-yl)disulfide, Enerion, S 5007, sulbuthiamine, sulbutiamin, sulbutiamine, Surmenalit
Storage Store at room temperature, tightly sealed, away from heat, light and moisture.
Solubility Soluble in DMSO
Organoleptic Profile White powder
Physical Form Solid
Specification ≥98%
Terms This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.

Lab Analysis

Sulbutiamine CoA Lot : 231129