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PPAP HCL Euro Nootropics


In Stock

Regular price €49,78

PPAP HCl, Powder ≥98%

PPAP is a catecholaminergic activity enhancer and mild atypical psychostimulant.

PPAP is a catecholaminergic activity enhancer (CAE) class research compound that selectively increases impulse propagation-mediated dopamine and norepinephrine release in response to action potentials. Unlike stimulant drugs, which release a flood of monoamine neurotransmitters in an uncontrolled manner, PPAP only increases the rate of neurotransmitter amine release that would be released in response to impulse-mediated neuron stimulation.

PPAP can be compared to stimulant drugs like amphetamine in that they both result in a net increase in the rate and magnitude of neurotransmitter release. However, this is where the comparison ends. Amphetamine and amphetamine-like compounds cause a ‘neurotransmitter dump’, in which large stores of neurotransmitter amines are ‘dumped’ into the synapses, regardless of external inputs. PPAP and its sister compounds do not alter the pattern of neurotransmitter release other than to increase the amount of neurotransmitter amines released, and only in response to external impulse mediation.


This Material is Sold For Research Use Only. Terms of Sale Apply. Not for Human Consumption, nor Medical, Veterinary, or Household Uses.


CAS Number: 42585-88-6
Purity: ≥99%
Molecular Weight: 152.58 g/mol
Melting Point: Unknown
Molecular Formula: C4H9ClN2O2•HCl
Synonyms: (±) 3-Amino-1-hydroxy-pyrrolidin-2-one; (±) 1-hydroxy-3-amino-pyrrolidone-2; R-(+)-HA-966 and S-(−)-HA-966
PubChem CID: 121225697


Application: (±) HA-966 is an atypical sedative, and neuroprotective antagonist/ weak partial agonist at the glycine modulatory site of the NMDA receptor complex.
Appearance: White or off-white powder
Physical State: Solid
Solubility: Soluble to 100 nM in water.
Storage: Store at room temperature or cooler, in a sealed airtight container, protected from heat, light and humidity.
Stability: Stable for at least two years when stored as above.

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