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Noopept

Noopept is a potent nootropic compound known for its ability to enhance memory, learning, and cognitive function. It is considered to be one of the most effective cognitive enhancers, often praised for its neuroprotective properties and its ability to improve focus, mental clarity, and mood.

For a more detailed description and lab analysis, please see the sections below.

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Noopept (Omberacetam), Powder

Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) is a synthetic nootropic that is structurally similar to the racetam family, particularly piracetam. However, Noopept is significantly more potent—up to 1000 times stronger than piracetam by weight—.

Noopept works by boosting acetylcholine and glutamate neurotransmission, both of which are critical for learning, memory formation, and mental clarity. It also offers neuroprotective benefits, such as reducing oxidative stress and protecting brain cells from damage. Many users report improved cognitive performance, enhanced memory, and better mental clarity when using Noopept regularly. Additionally, Noopept has been studied for its potential to improve mood and reduce anxiety by modulating neurotransmitter levels.

Mechanism of Action:

Noopept works by modulating key neurotransmitters in the brain, particularly acetylcholine and glutamate. By increasing the activity of these neurotransmitters, Noopept enhances synaptic plasticity, supporting learning, memory retention, and overall cognitive performance.

  • Acetylcholine: Noopept enhances cholinergic activity, which is essential for memory formation, attention, and learning.
  • Glutamate: It also influences the AMPA receptors in the glutamatergic system, which play a critical role in long-term potentiation (LTP) and synaptic plasticity. This leads to improved memory and cognitive function.
  • Neuroprotection: Noopept has neuroprotective properties, such as reducing oxidative stress and preventing damage from neurotoxicity. This helps maintain healthy brain function over time.

Benefits:

  • Memory Enhancement: Noopept is particularly effective at improving both short-term and long-term memory, as well as memory recall. This makes it highly beneficial for tasks involving information retention and retrieval.
  • Improved Focus and Mental Clarity: Many users report enhanced focus and clearer thinking, especially when performing cognitively demanding tasks. Noopept’s effects on neurotransmitter systems help sharpen attention and reduce mental fog.
  • Mood and Anxiety Relief: Noopept has shown potential in reducing anxiety and improving mood by regulating neurotransmitters like serotonin and dopamine, which play roles in mood stabilization and emotional well-being.
  • Neuroprotection: Noopept’s ability to protect neurons from oxidative stress and other forms of damage makes it useful for supporting long-term brain health and potentially reducing age-related cognitive decline.

Clinical Research:

  • Memory and Cognition: Studies, such as those by Ostrovskaya et al. (2002), have shown that Noopept improves memory performance, cognitive function, and learning abilities in both healthy individuals and those with cognitive impairments.
  • Mood and Anxiety: Research on Noopept’s effects, such as in studies conducted by Neznamov and Teleshova (2009), suggests that the compound can reduce anxiety and improve mood in individuals suffering from emotional and cognitive disturbances.

Additional Effects:

  • Cognitive Longevity: Long-term cognitive health and protection against age-related decline.
  • Enhanced Sensory Perception: Improvements in sensory perception (such as enhanced sound and visual clarity), which may be linked to Noopept’s effects on neurotransmitter systems.

Safety and Considerations:

Noopept is well-tolerated  when taken at the recommended doses. However, side effects such as headaches, irritability, or nausea may occur, especially if taken in excessive amounts. Taking a choline supplement may also help reduce headaches associated with increased acetylcholine activity.

For a detailed lab analysis and comprehensive product specifications, please refer to the sections below.

 

Description

Noopept (Omberacetam), Powder

Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) is a synthetic nootropic that is structurally similar to the racetam family, particularly piracetam. However, Noopept is significantly more potent—up to 1000 times stronger than piracetam by weight—.

Noopept works by boosting acetylcholine and glutamate neurotransmission, both of which are critical for learning, memory formation, and mental clarity. It also offers neuroprotective benefits, such as reducing oxidative stress and protecting brain cells from damage. Many users report improved cognitive performance, enhanced memory, and better mental clarity when using Noopept regularly. Additionally, Noopept has been studied for its potential to improve mood and reduce anxiety by modulating neurotransmitter levels.

Mechanism of Action:

Noopept works by modulating key neurotransmitters in the brain, particularly acetylcholine and glutamate. By increasing the activity of these neurotransmitters, Noopept enhances synaptic plasticity, supporting learning, memory retention, and overall cognitive performance.

  • Acetylcholine: Noopept enhances cholinergic activity, which is essential for memory formation, attention, and learning.
  • Glutamate: It also influences the AMPA receptors in the glutamatergic system, which play a critical role in long-term potentiation (LTP) and synaptic plasticity. This leads to improved memory and cognitive function.
  • Neuroprotection: Noopept has neuroprotective properties, such as reducing oxidative stress and preventing damage from neurotoxicity. This helps maintain healthy brain function over time.

Benefits:

  • Memory Enhancement: Noopept is particularly effective at improving both short-term and long-term memory, as well as memory recall. This makes it highly beneficial for tasks involving information retention and retrieval.
  • Improved Focus and Mental Clarity: Many users report enhanced focus and clearer thinking, especially when performing cognitively demanding tasks. Noopept’s effects on neurotransmitter systems help sharpen attention and reduce mental fog.
  • Mood and Anxiety Relief: Noopept has shown potential in reducing anxiety and improving mood by regulating neurotransmitters like serotonin and dopamine, which play roles in mood stabilization and emotional well-being.
  • Neuroprotection: Noopept’s ability to protect neurons from oxidative stress and other forms of damage makes it useful for supporting long-term brain health and potentially reducing age-related cognitive decline.

Clinical Research:

  • Memory and Cognition: Studies, such as those by Ostrovskaya et al. (2002), have shown that Noopept improves memory performance, cognitive function, and learning abilities in both healthy individuals and those with cognitive impairments.
  • Mood and Anxiety: Research on Noopept’s effects, such as in studies conducted by Neznamov and Teleshova (2009), suggests that the compound can reduce anxiety and improve mood in individuals suffering from emotional and cognitive disturbances.

Additional Effects:

  • Cognitive Longevity: Long-term cognitive health and protection against age-related decline.
  • Enhanced Sensory Perception: Improvements in sensory perception (such as enhanced sound and visual clarity), which may be linked to Noopept’s effects on neurotransmitter systems.

Safety and Considerations:

Noopept is well-tolerated  when taken at the recommended doses. However, side effects such as headaches, irritability, or nausea may occur, especially if taken in excessive amounts. Taking a choline supplement may also help reduce headaches associated with increased acetylcholine activity.

For a detailed lab analysis and comprehensive product specifications, please refer to the sections below.

 

Lab Analysis

 


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COA_Noopept_2024-04-17
2211EURO.163g Noopept_CoA
2211EURO.163G_Noopept CAS=157115-85-0 Lot=121022

Chemical Informations

Technical Information
CAS Number 157115-85-0
PubChem CID 180496
Purity ≥98%
Molecular Weight 318.367 g/mol
Molecular Formula C₁₇H₂₂N₂O₄
Melting Point 97°C-98°C
Synonyms N-phenylacetyl-L-prolylglycine ethyl ester, GVS-111
SMILES Notation c2ccccc2CC(=O)N1CCC[C@@H]1C(=O)NCC(=O)OCC
Application A nootropic agent derived from the racetam family. Stimulates the expression of NGF and BDNF in rat hippocampus.
Appearance White powder
Physical State Solid
Solubility – Soluble to 25 mM in Ethanol
– Sparingly soluble in Water
Storage Conditions Store at room temperature or cooler, in a sealed airtight container, protected from heat, light, and humidity.
Stability Stable for at least two years when stored as above.

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