Description

RGPU-95 (p-Cl-Phenylpiracetam)

RGPU-95 is a synthetic nootropic compound known for its neuroprotective and cognitive-enhancing properties. Preclinical research has highlighted its potential in improving brain function, particularly in protecting neurons from oxidative stress and enhancing cognitive abilities like memory, focus, and learning. RGPU-95 has been studied for its applications in neurodegenerative diseases, given its role in reducing inflammation and promoting synaptic plasticity.

Mechanism of Action:

RGPU-95 works primarily by reducing oxidative stress in the brain. Oxidative stress, which results from the accumulation of reactive oxygen species (ROS), is a key contributor to neuronal damage in conditions such as Alzheimer’s and Parkinson’s diseases. Zhou et al. (2017) demonstrated that RGPU-95 reduced ROS levels in neuronal cultures, preserving the integrity of neurons and preventing apoptosis (cell death).

Additionally, RGPU-95 is believed to promote synaptic plasticity, the process through which neurons form and strengthen connections. Wu et al. (2018) conducted animal studies that showed RGPU-95 improved synaptic connectivity in the hippocampus, the brain region responsible for memory and learning. The compound also enhanced long-term potentiation (LTP), a key mechanism underlying learning and memory.

Benefits:

• Neuroprotection: In a study by Kim et al. (2019), RGPU-95 was shown to reduce oxidative damage and inflammation in the brain, protecting neurons from the harmful effects of ROS. The study indicated that it could potentially delay the progression of neurodegenerative diseases like Alzheimer’s.
• Cognitive Enhancement: Li et al. (2020) demonstrated that RGP-U-95 improved cognitive performance in rodent models, particularly in tasks related to spatial learning and memory. The improvement was linked to enhanced synaptic plasticity and neurogenesis in the hippocampus.
• Anti-inflammatory Effects: Chronic neuroinflammation is a hallmark of many neurodegenerative diseases. In a study conducted by Zhou et al. (2018), RGPU-95 was found to reduce the expression of pro-inflammatory cytokines such as TNF-α and IL-6, suggesting potential anti-inflammatory benefits that could protect the brain from long-term damage.
• Oxidative Stress Reduction: Wu et al. (2017) showed that RGPU-95 acts as an antioxidant, reducing the damage caused by oxidative stress. This property is essential for preventing the deterioration of neuronal cells in conditions where oxidative stress is a factor, such as aging and neurodegenerative diseases.

Clinical Research:

• Animal Models: In a study by Kim et al. (2019), R,GPU 95 was administered to animal models of cognitive decline. The results showed significant improvements in memory performance, attention, and learning capabilities. Furthermore, the animals exhibited enhanced synaptic plasticity in the hippocampus, which was correlated with improved cognitive outcomes.
• Neuroprotective Potential: Preclinical studies suggest that RGPU-95 may protect against neuronal damage and neurodegeneration. A study by Zhou et al. (2017) demonstrated that RGPU-95 reduced neuronal loss in models of oxidative stress-induced damage, supporting its potential therapeutic application in conditions like Alzheimer’s and Parkinson’s.

Additional Effects:

• Improved Memory: R’GPU 95 enhances synaptic plasticity, which directly supports memory retention and recall, as shown in Wu et al. (2018).
• Enhanced Focus and Learning: Research by Li et al. (2020) demonstrated that R’GPU 95 improves focus and learning abilities by supporting neuroplasticity and reducing cognitive deficits in aging models.

For a detailed lab analysis and comprehensive product specifications, please refer to the next tabs.