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Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) delivered in vegetarian capsules. As a dimer combining two modified thiamine molecules, it readily crosses the blood–brain barrier thus increasing levels of thiamine and thiamine phosphate esters in the brain. Sulbutiamine was developed in Japan by Taisho Pharmaceutical in 1965.
Sulbutiamine is a psychostimulant, the anti-asthenic and energising effects of which are the result of modification of the thiamine ring, the formation of a disulphide bridge, creation of a lipophilic ester and opening of the thiazole cycle. The resulting new lipophilic compound is therefore responsible for its valuable properties. Sulbutiamine’s main benefit lies in its ability to combat asthenia by selectively targeting the areas involved in the condition. Asthenia is essentially a form of chronic fatigue that is cerebral rather than neuromuscular in origin.
| Size | 20g, 50g |
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| Application | Dopamine modulator, lipophilic derivative of thiamine |
| CAS | 3286-46-2 |
| Molar Mass | 702.9 g/mol |
| Chemical Formula | C32H46N8O6S2 |
| IUPAC Name | [(Z)-4-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-3-[[(Z)-2-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-5-(2-methylpropanoyloxy)pent-2-en-3-yl]disulfanyl]pent-3-enyl] 2-methylpropanoate |
| Synonyms | 2-isobutyrylthiamine disulfide, Arcalion, bis(2-(isobutyryloxy)ethyl-1-N-((4-amino-2-methylpyrimidin-5-yl)methyl)formamido-2-propene-1-yl)disulfide, Enerion, S 5007, sulbuthiamine, sulbutiamin, sulbutiamine, Surmenalit |
| Storage | Store at room temperature, tightly sealed, away from heat, light and moisture. |
| Solubility | Soluble in DMSO |
| Organoleptic Profile | White powder |
| Physical Form | Solid |
| Specification | ≥98% |
| Terms | This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering. |
