Dihexa

Dihexa is a synthetic nootropic compound known for its potential to promote neurogenesis and enhance synaptogenesis, which are critical for improving cognitive function, memory, and learning. Dihexa has been researched for its ability to help repair brain damage and support cognitive performance, particularly in neurodegenerative conditions.

For a more detailed description and lab analysis, please see the sections below.

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Dihexa, Powder

Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a potent neurotrophic compound, meaning it promotes the growth and repair of neurons in the brain. Originally developed to treat neurodegenerative diseases like Alzheimer’s, Dihexa is a peptide-based compound that enhances brain-derived neurotrophic factor (BDNF) and supports synaptic plasticity. These actions are critical for memory formation, learning, and overall cognitive function. It has been developed by researchers from Washington State University to potently improve certain cognitive function of potential trauma-based brain disorders and neurodegenerative conditions such as Alzheimer’s through increased synaptogenesis. Dihexa could perhaps be used to accelerate wound healing, promote improvement of circulation, and perhaps even enhance anabolic development and prevent muscular atrophy.

Dihexa is unique in its ability to cross the blood-brain barrier easily, allowing it to interact directly with brain cells. Research has shown that Dihexa may improve the formation of new synapses, which is essential for maintaining and enhancing cognitive performance, particularly in individuals with cognitive impairments or age-related cognitive decline.

The Dihexa we offer is lyophilized Dihexa, ensuring maximum stability, potency, and long shelf life for your research needs. The freeze-drying process preserves the compound’s bioactivity by protecting it from heat, moisture, and degradation, making it ideal for long-term storage and easy transportation. With lyophilized Dihexa, you benefit from flexible reconstitution options, allowing for precise use and optimal absorption, while minimizing the risk of contamination and maintaining the highest quality for effective research applications.

Mechanism of Action:

Dihexa works by enhancing hepatocyte growth factor (HGF), a molecule involved in promoting neurogenesis and synaptogenesis. HGF is a key factor in the growth, repair, and maintenance of neurons, and It’s ability to potentiate its activity makes it highly effective for improving brain function.

  • Neurogenesis: Dihexa promotes the growth of new neurons, supporting brain health, cognitive resilience, and repair after injury.
  • Synaptogenesis: The compound enhances synapse formation, which improves communication between neurons, supporting learning, memory, and cognitive performance.

Effects:

  • Cognitive Enhancement: Dihexa is known for its ability to improve memory, learning, and cognitive function by promoting neurogenesis and synaptogenesis.
  • Neuroprotection: The compound may protect against age-related cognitive decline and neurodegenerative diseases by repairing damaged neurons and promoting brain cell health.
  • Memory Improvement: It has been studied for its potential to significantly improve memory retention and recall, making it a promising option for enhancing both short-term and long-term memory.
  • Potential in Neurodegenerative Diseases: Research suggests that Dihexa could be beneficial for conditions like Alzheimer’s and Parkinson’s disease, where neurodegeneration and synaptic loss are prevalent.

Clinical Research:

  • Neurogenesis and Synaptogenesis: Studies on Dihexa have shown significant promotion of synaptogenesis and neurogenesis. Research by Benoist et al. (2015) indicated that It enhanced synaptic plasticity and improved cognitive performance in animal models.
  • Alzheimer’s and Neuroprotection: Research by Wright et al. (2012) demonstrated that It could improve cognitive function in models of Alzheimer’s disease by promoting neuronal repair and synapse formation, suggesting its potential as a therapeutic for neurodegenerative conditions.

Additional Effects:

  • Mood Stabilization: Though not its primary function, the neuroprotective effects of Dihexa may also contribute to mood stabilization and mental clarity.
  • Recovery from Brain Injury: Due to its neurogenic properties, Dihexa has been researched for its potential in supporting recovery after traumatic brain injuries or stroke.

For detailed lab analysis and product specifications, please refer to the next tabs.

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Description

Dihexa, Powder

Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a potent neurotrophic compound, meaning it promotes the growth and repair of neurons in the brain. Originally developed to treat neurodegenerative diseases like Alzheimer’s, Dihexa is a peptide-based compound that enhances brain-derived neurotrophic factor (BDNF) and supports synaptic plasticity. These actions are critical for memory formation, learning, and overall cognitive function. It has been developed by researchers from Washington State University to potently improve certain cognitive function of potential trauma-based brain disorders and neurodegenerative conditions such as Alzheimer’s through increased synaptogenesis. Dihexa could perhaps be used to accelerate wound healing, promote improvement of circulation, and perhaps even enhance anabolic development and prevent muscular atrophy.

Dihexa is unique in its ability to cross the blood-brain barrier easily, allowing it to interact directly with brain cells. Research has shown that Dihexa may improve the formation of new synapses, which is essential for maintaining and enhancing cognitive performance, particularly in individuals with cognitive impairments or age-related cognitive decline.

The Dihexa we offer is lyophilized Dihexa, ensuring maximum stability, potency, and long shelf life for your research needs. The freeze-drying process preserves the compound’s bioactivity by protecting it from heat, moisture, and degradation, making it ideal for long-term storage and easy transportation. With lyophilized Dihexa, you benefit from flexible reconstitution options, allowing for precise use and optimal absorption, while minimizing the risk of contamination and maintaining the highest quality for effective research applications.

Mechanism of Action:

Dihexa works by enhancing hepatocyte growth factor (HGF), a molecule involved in promoting neurogenesis and synaptogenesis. HGF is a key factor in the growth, repair, and maintenance of neurons, and It’s ability to potentiate its activity makes it highly effective for improving brain function.

  • Neurogenesis: Dihexa promotes the growth of new neurons, supporting brain health, cognitive resilience, and repair after injury.
  • Synaptogenesis: The compound enhances synapse formation, which improves communication between neurons, supporting learning, memory, and cognitive performance.

Effects:

  • Cognitive Enhancement: Dihexa is known for its ability to improve memory, learning, and cognitive function by promoting neurogenesis and synaptogenesis.
  • Neuroprotection: The compound may protect against age-related cognitive decline and neurodegenerative diseases by repairing damaged neurons and promoting brain cell health.
  • Memory Improvement: It has been studied for its potential to significantly improve memory retention and recall, making it a promising option for enhancing both short-term and long-term memory.
  • Potential in Neurodegenerative Diseases: Research suggests that Dihexa could be beneficial for conditions like Alzheimer’s and Parkinson’s disease, where neurodegeneration and synaptic loss are prevalent.

Clinical Research:

  • Neurogenesis and Synaptogenesis: Studies on Dihexa have shown significant promotion of synaptogenesis and neurogenesis. Research by Benoist et al. (2015) indicated that It enhanced synaptic plasticity and improved cognitive performance in animal models.
  • Alzheimer’s and Neuroprotection: Research by Wright et al. (2012) demonstrated that It could improve cognitive function in models of Alzheimer’s disease by promoting neuronal repair and synapse formation, suggesting its potential as a therapeutic for neurodegenerative conditions.

Additional Effects:

  • Mood Stabilization: Though not its primary function, the neuroprotective effects of Dihexa may also contribute to mood stabilization and mental clarity.
  • Recovery from Brain Injury: Due to its neurogenic properties, Dihexa has been researched for its potential in supporting recovery after traumatic brain injuries or stroke.

For detailed lab analysis and product specifications, please refer to the next tabs.

Additional information

Size

500mg, 1g

Lab Analysis


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COA_Dihexa_2024-03-05
2301EURO.634B_DIHEXA cas= 1401708-83-5 LOT=180223
2304EURO.993L_Dihexa CAS=1401708-83-5 LOT230423

Chemical Informations

Technical Information
CAS Number 1401708-83-5
Molar Mass 504.67 g/mol
Chemical Formula C₂₇H₄₄N₄O₅
IUPAC Name (2S,3S)-N-(6-amino-6-oxohexyl)-2-[[(2S)-2-(hexanoylamino)-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanamide
Synonyms N-hexanoic-Tyr-Ile-(6) aminohexanoic amide,
Dihexa, UNII-9WYX65A5C2, 9WYX65A5C2, 1401708-83-5,
PNB-0408, ZINC605699141, CS-6864, HY-16969,
L-Isoleucinamide, N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-,
6-(2-(2-Hexanamido-3-(4-hydroxyphenyl)propanamido)-3-methylpentanamido)hexanamide
Application c-Met Receptor Agonist
Appearance White powder
Physical State Solid
Purity ≥98%
Solubility – Soluble in DMSO
– Soluble in PEG400
Storage Conditions Store in a dry, dark place at -20°C for up to two years, tightly sealed, away from heat, light, and moisture.
Terms of Use This material is sold for laboratory research use only. Terms of sale apply.

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