Atypical sedative, and neuroprotective antagonist at the glycine modulatory site of the NMDA receptor complex. It has neuroprotective and anticonvulsant, anxiolytic, antinociceptive and sedative / hypnotic effects in animal models. Pilot human clinical trials in the early 1960s showed that HA-966 appeared to benefit patients with tremors of extrapyramidal origin.
PRECAUTION AND DISCLAIMER:
This Material is Sold For Research Use Only. Terms of Sale Apply. Not for Human Consumption, nor Medical, Veterinary, or Household Uses.
(±) 3-Amino-1-hydroxy-pyrrolidin-2-one; (±) 1-hydroxy-3-amino-pyrrolidone-2; R-(+)-HA-966 and S-(−)-HA-966
(±) HA-966 is an atypical sedative, and neuroprotective antagonist/ weak partial agonist at the glycine modulatory site of the NMDA receptor complex.
White or off-white powder
Soluble to 100 nM in water.
Store at room temperature or cooler, in a sealed airtight container, protected from heat, light and humidity.
Stable for at least two years when stored as above.
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